| 风湿性疾病患者膝关节液中铜锌超氧化物歧化酶的测定 |
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| 引用本文： | 于孟学,史立,张春芳,李培峰.风湿性疾病患者膝关节液中铜锌超氧化物歧化酶的测定[J].河北北方学院学报(医学版),1994(3). |
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| 作者姓名： | 于孟学 史立 张春芳 李培峰 |
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| 作者单位： | 中国医学科学院中国协和医科大学北京协和医院，中国医学科学院中国协和医科大学北京协和医院，中国医学科学院中国协和医科大学北京协和医院，中国医学科学院中国协和医科大学北京协和医院 北京 100730，北京 100730，北京 100730，北京 100730 |
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| 摘 要： | 应用酶联免疫吸附法(ELISA)测定32例风湿性疾病患者膝关节滑膜液的铜锌超氧化物歧化酶(CuZn-SOD),以OD0.1为界,反应性关节炎(ReA)5例均低于0.1;类风湿关节炎(RA)11例中4例低于0.1,均为急性炎症;骨性关节炎(OA)16例,均高于0.1,以ReA及RA为一组,与OA组之间作统计学(X~2)处理,明显低于OA组,差异非常显著。表明了活性氧是急性风湿性疾病关节内的炎性介质之一。
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| 关 键 词： | 关节炎 类风湿性 风湿病 滑膜液 铜锌超氧化物歧化酶 活性氧 |
CuZn-SOD DETERMINATION OF KNEE SYNOVIAL FLUID IN THE PATIENTS WITH RHEUMATIC DISEASES |
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| Yu Meng-xue.CuZn-SOD DETERMINATION OF KNEE SYNOVIAL FLUID IN THE PATIENTS WITH RHEUMATIC DISEASES[J].Journal of Hebei North University:Medical Edition,1994(3). |
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| Authors: | Yu Meng-xue |
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| Institution: | Yu Meng-xue |
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| Abstract: | We used Enzyme Linked Immuno-Sorbent Assay (ELISA) to measure Cu Zn superoxide dismutases (Cu Zn-SOD)of knee synovial fluid in 32 patients with rheumatic diseases. OD0.1 was regarded as border value, lower than that in 5cases of reactive arthritis (ReA) and in 4 of 11 cases of rheumatoid arthritis (RA), higher than that in 16 cases of osteoarthritis(OA), CuZn-SOD contents were lower in ReA RA group than in OA group with obviously statistical difference.It is suggested that oxy radical is one of the inflammatory mediators in the jointsof patients with acute rheumatic diseases. |
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| Keywords: | arthrfts: rheumatoid rheumatism synovial fluid CuZn superoxide dismutase (CuZn-SOD) oxy radicals |
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