补充大豆低聚肽对高强度运动后大鼠肠道粘膜屏障的影响 |
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引用本文: | 李世成,李跃纲,王启荣,杨则宜,李肃反.补充大豆低聚肽对高强度运动后大鼠肠道粘膜屏障的影响[J].武汉体育学院学报,2009,43(4):39. |
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作者姓名: | 李世成 李跃纲 王启荣 杨则宜 李肃反 |
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作者单位: | 1. 湛江师范学院体育科学学院,广东湛江,524048 2. 北京市疾病控制中心,北京,100027 3. 国家体育总局运动医学研究所,北京,100029 |
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基金项目: | 国家科技攻关计划-奥运科技专项课题 |
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摘 要: | 研究目的:补充大豆低聚肽对大鼠小肠上皮组织形态学和IEL的影响,观察大豆低聚肽对高强度运动后肠道粘膜屏障的保护作用.方法:雄性SD大鼠40只,被随机分为灌喂水安静(A)组、灌喂大豆低聚肽安静(B)组、灌喂水运动(C)组和灌喂大豆低聚肽运动(D)组.大鼠在适应性喂养及膳食平衡1周后,进行实验及指标测试.结果:高强度运动后,大鼠肠道粘膜机械屏障出现轻微损伤和IEL减少,而补充大豆低聚肽后,与C组比较,D组大鼠小肠粘膜厚度增高33.36%(P<0.05),小肠绒毛高度增高12.91%(P<0.05),小肠粘膜隐窝深度增加32.84%(P<0.05),IEL增加40.96%(P<0.05).结论:补充大豆低聚肽可改善高强度运动后小肠粘膜屏障功能.
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关 键 词: | 大豆低聚肽 高强度运动 小肠粘膜屏障 大鼠 |
Effects of soy ol igopeptides supplemention on small intestinal
mucosa barrier af ter high intensity exercise in rats |
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Abstract: | This paper was to study the effect s of soy oligopeptides supplementation on small intestinal mucosa
barrier after high intensity exercise. Forty male SD rat s were randomly divided into four groups , Group A (no
training and water supplemented) , Group B ( no training and soy oligopeptides supplemented) , Group C
(training and water supplemented) , Group D (training and soy oligopeptides supplemented) . After one week
meal adaption , small intestinal morphology were determined. It was shown that the small intestinal mucosa
barrier were injured slightly after high intensity exercise. The mucosal thickness in Group D increased by 33.
36 % (p < 0. 05) than that of Group C. And the villous height increased by 12. 91 % ( p < 0. 05) , the crypt
depth by 32. 84 % ( p < 0. 05) and IEL by 40. 96 % ( p < 0. 05) . It was proved that soy oligopeptides could im2
prove the the small intestinal mucosa barrier after high intensity exercise. |
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Keywords: | soy olipeoptides high intensity exercise small intestinal mucosa barrier rat |
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