Curcumin inhibits proliferation of human lens epithelial cells: a proteomic analysis |
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Authors: | Yan-hong Hu Xiu-rong Huang Ming-xin Qi and Bu-yuan Hou |
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Institution: | 1Department of Ophthalmology, the Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou 350003, China;2Research Center of Pathophysiology, Fujian University of Traditional Chinese Medicine, Fuzhou 350003, China |
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Abstract: | Objective The incidence of after-cataracts also known as posterior capsular opacification (PCO)] is between 30% and 50% three years
following cataract surgery. Suppressing the proliferation of lens epithelial cells (LECs) is a primary goal in preventing
PCO. Here, we investigated the proteomic regulation of the inhibitory effects of curcumin (Cur) on the proliferation of human
lens epithelial B3 (HLE-B3) cells. |
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Keywords: | Curcumin After-cataract Posterior capsular opacification (PCO) Proteomics Lens epithelial cells |
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