The development and maintenance of odor-based double-alternation responding under conditions of Thorazine and Elavil injection |
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| Authors: | Stephen F Davis Roger L Thomas Robert E Prytula |
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| Institution: | 1. Emporia State University, 66801, Emporia, Kansas
2. Middle Tennessee State University, 37132, Murfreesboro, Tennessee
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| Abstract: | Two experiments investigating odor production and utilization in rats under the effects of Thorazine and Elavil injections, respectively, are reported. In Experiment 1, significantly slower speeds shown by the Thorazine-injected subjects indicated that this drug depressed performance. It is felt that depressed performance allowed these subjects to attend and respond to odor cues earlier in Phase 1 than did saline-injected control animals. Reversing the injection conditions (Phase 2) failed to disrupt already-established patterning. During the first phase of Experiment 2, Elavil-injected subjects failed to establish patterned responding, whereas such responding was readily established by saline-injected subjects. Reversing the injection conditions (Phase 2) resulted in the rapid development of double-alternation patterning by the subjects that were shifted from Elavil to saline and in the maintenance of such responding by the animals shifted from saline to Elavil. |
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