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Immunomodulative effects of mesenchymal stem cells derived from human embryonic stem cells in vivo and in vitro |
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| Authors: | Tan Zhou Su Zhong-yuan Wu Rong-rong Gu Bin Liu Yu-kan Zhao Xiao-li Zhang Ming |
| Institution: | Institute of Cell Biology and Genetics, College of Life Sciences, Zhejiang University, Hangzhou 310058, China. |
| Abstract: | ObjectiveHuman embryonic stem cells (hESCs) have recently been reported as an unlimited source of mesenchymal stem cells (MSCs). The present study not only provides an identical and clinically compliant MSC source derived from hESCs (hESC-MSCs), but also describes the immunomodulative effects of hESC-MSCs in vitro and in vivo for a carbon tetrachloride (CCl4)-induced liver inflammation model. |
| Keywords: | Human embryonic stem cells Mesenchymal stem cells Differentiation Immunomodulative effects |
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