Attenuation of the CS-preexposure effect after a retention interval in preweanling rats |
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| Authors: | Philipp J Kraemer Heather Hoffmann Norman E Spear |
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| Institution: | 1. Center for Developmental Psychobiology, Department of Psychology, University Center at Binghamton-SUNY, 13901, Binghamton, NY
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| Abstract: | The effects of flavor preexposure and retention interval were assessed in 6- and 12-day-old rats. Conditioned aversions to a flavor appeared at both ages. The conditioning of the younger pups was unaffected by conditioned stimulus (CS) preexposure and was not evident after a 10-day retention interval. For the 12-day-old rats, preexposure to either the flavor CS or a different flavor attenuated aversion strength when the rats were tested soon after conditioning. Other 12-day-old rats that were tested 10 days after conditioning also expressed substantial aversions, but with a retention interval of this length, the aversions were equivalent for animals preexposed to the CS and those not preexposed before conditioning. This loss of the CS-preexposure effect over a long interval, which has also been observed in adult rats, identifies the locus of this effect as postacquisition and perhaps at the stage of memory retrieval. |
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