| 细胞内铜途径:铜伴侣蛋白的作用 |
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| 引用本文： | 郭彤,许梓荣.细胞内铜途径:铜伴侣蛋白的作用[J].科技通报,2004,20(1):73-76. |
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| 作者姓名： | 郭彤 许梓荣 |
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| 作者单位： | 浙江大学饲料研究所,教育部分子营养学重点实验室,杭州,310029 |
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| 摘 要： | 铜是生物体必需的微量元素，目前发现，体内铜平衡机制是蛋白质介导的，它将细胞内的铜传递给靶蛋白。这一途径是通过新的蛋白质家族——铜伴侣蛋白实现的．铜伴侣蛋白对细胞内铜途径有重要作用。介绍了金属伴侣蛋白的功能、结构特点及铜伴侣蛋白的作用。
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| 关 键 词： | 铜 微量元素 铜伴侣蛋白 细胞内传递 传递途径 平衡机制 |
| 文章编号： | 1001-7119(2004)01-0073-04 |
| 修稿时间： | 2002年11月15 |
Intracellular Copper Routing:The Role of Copper Chaperones |
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| GUO Tong,XU Zi-rong eed Science Institute of Zhejiang University,Hangzhou ,China.Intracellular Copper Routing:The Role of Copper Chaperones[J].Bulletin of Science and Technology,2004,20(1):73-76. |
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| Authors: | GUO Tong XU Zi-rong eed Science Institute of Zhejiang University Hangzhou China |
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| Institution: | GUO Tong,XU Zi-rong eed Science Institute of Zhejiang University,Hangzhou 310029,China) |
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| Abstract: | Copper is required by all living systems. Cells have a variety of mechanisms to deal with this essential, toxic trace element. A recently discovered homeostatic mechanism is the protein-mediated, intracellular delivery of copper to target proteins. Copper chaperones play an important role in intracellular copper routing. The function and structure of metallochaperone and copper chaperones were summarized. |
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| Keywords: | copper chaperones intracellular delivery routing |
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