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Jacobus Henricus van’ t Hoff
Authors:G Nagendrappa
Institution:(1) # 13, Basappa Layout Gavipuram Extension, Bangalore, 560 019, India
Abstract:J H van’ t Hoff is considered as one of the greatest chemists of all time. He started his career as an organic chemist. He solved the vexing problem of optical isomerism by proposing an asymmetric tetrahedral carbon bonded to form different groups. He extended this to include geometric isomerism, and to compounds with heteroatoms in place of asymmetric carbon. Thus he established the ‘chemistry in space’ or stereochemistry. He moved on to work on reaction kinetics, equilibria, thermodynamic properties of dilute solutions and related areas. He laid the foundation for physical chemistry through these discoveries and was awarded the first Nobel Prize in Chemistry in 1901. van’ t Hoff died of tuberculosis at a relatively early age of 59.
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