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Effect of short term vitamin E supplementation on lipid peroxidation in acute myocardial infarction
Authors:A P Jain  A Mohan  O P Gupta  U N Jajoo  S P Kalantri  L M Srivastava
Institution:(1) Dept. of Medicine, Mahatma Gandhi Institute of Medical Sciences, Sevagram, 442102 Wardha;(2) Dept of Biochemistry, All India Institute of Medical Sciences, 110029 New Delhi
Abstract:In view of sufficient body of evidence to substantiate the role of free radical mediated oxidative injury in myocardial infarction (M.I.), the utility of exogenous supplementation with antioxidant substance, vitamin E was studied. Forty patients of acute myocardial infarction were divided into two equal groups, one who received vitamin E and the other who did not. Plasma MDA levels showed a reduction in patients of M.I. who received vitamin E as well as in those who did not, however, the decrease was significantly more in the vitamin E treated subgroup.
Keywords:Vitamin E  Lipid peroxidation  Myocardial infarction
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