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Spontaneous retroperitoneal hemorrhage after hemodialysis involving anticoagulant agents
Authors:Wen-xing Fan  Zheng-xu Deng  Fang Liu  Rong-bo Liu  Ling He  Bogati Amrit  Li Zang  Jing-wen Li  Xian-rong Liu  Song-min Huang  Ping Fu
Institution:1Department of Nephrology, West China Hospital, Sichuan University, Chengdu 610041, China;2Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China
Abstract:In this paper, we described the symptoms and treatment of a patient with diabetic nephropathy accompanied by spontaneous retroperitoneal hemorrhage after hemodialysis. An elderly female patient with diabetic nephropathy presented with severe pain, numbness, and an increasing swelling in the left hip and left thigh after six sessions of hemodialysis involving the use of an antiplatelet drug and an anticoagulant agent. Her hemoglobin decreased to 46 g/L. An abdominal ultrasound showed a hematoma in the left retroperitoneal space, and computed tomography (CT) findings revealed a 6 cm×8 cm×10 cm hematoma in the left psoas muscle. After aggressive supportive therapy the administration of packed red blood cell transfusion, carbazochrome sodium sulfonate injection, and continuous venovenous hemofiltration (CVVH)], the patient’s vital signs stabilized and her hemoglobin increased to 86 g/L. Repeat CT showed that the hematoma had been partially absorbed after two weeks. Eventually, the patient was discharged with stable vital signs. Physicians should be aware of the possibility of spontaneous retroperitoneal hemorrhage, particularly in patients with diabetic nephropathy undergoing hemodialysis involving the use of anticoagulant agents.
Keywords:Spontaneous retroperitoneal hemorrhage  Diabetic nephropathy  Hemodialysis  Nadroparin calcium
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