| 金樱子多糖体外抗脂质过氧化和红细胞溶血作用研究 |
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| 引用本文： | 皮建辉,胡朝暾,郑晴,蔡婧.金樱子多糖体外抗脂质过氧化和红细胞溶血作用研究[J].怀化师专学报,2012(5):11-15. |
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| 作者姓名： | 皮建辉 胡朝暾 郑晴 蔡婧 |
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| 作者单位： | [1]怀化学院．民族药用植物资源研究与利用湖南省重点实验室 [2]湘西药用植物与民族植物学湖南省高校重点实验室 [3]生命科学系,湖南怀化418008 |
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| 基金项目： | 民族药用植物资源研究与利用湖南省重点实验室委托项目（HHUW2010-71）. |
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| 摘 要： | 采用体外实验研究了金樱子多糖（RP）对小鼠肝脏自发性脂质过氧化、H2O2诱导的脂质过氧化、Fe^2＋-Vc诱导的肝线粒体氧化损伤和H2O2诱导的红细胞氧化溶血的影响，比较了金樱子多糖和维生素C（Vc）的抗脂质过氧化作用．结果表明：金樱子多糖具有较强的体外抗脂质过氧化作用，且呈现良好的量效关系；其抗氧化活性明显高于维生素C．
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| 关 键 词： | 金樱子多糖 脂质过氧化 红细胞溶血 抗氧化活性 |
Studies on the Effects of Polysaccharide from Rosa Lacvigata Michx in Anti- lipoperoxidant and Anti- erythrocyte Haemolysis in Vitro |
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| Institution: | PI Jian - hui , HU Chao - tun , ZHENG Qing , CAI Jin ( 1. Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources ; 2. Laboratory of Hunan Higher Education for Hunan - western Medicinal Plant and Ethnobotany ; 3. Department of Life Science, Huaihua University, Huaihua , Hunan 418008 ) |
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| Abstract: | In this paper, the effects of Rosa Lacvigata Polysaccharide （RP） in the spontaneous lipid peroxidation, the lipid peroxidation and erythrocyte haemolysis induced by H2O2 , and mitochondrial oxidative damage induced by Fe^2＋ - Vc in mice liver were studied, in vitro. And the anti - lipoperoxidation of RP was compared to that of Vc. The results indicated that RP has strong vitro function on anti - lipoperoxidation, and there was obviously dose - effect relationship between activity and concentration. And the antioxidant activity of RP was obviously stronger than that of Vc. |
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| Keywords: | Rosa Lacvigata polysaccharide lipid peroxidation erythrocytic hemolysis anti - oxidative activity |
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