Pure word deafness associated with extrapontine myelinolysis |
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| Authors: | Zhu Ren-jing Lv Zhi-su Shan Chun-lei Xu Ming-wei Luo Ben-yan |
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| Institution: | (1) Department of Internal Medicine, Hualien Armed Forces General Hospital, Hualien, Taiwan, ROC;(2) Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sect. 2, Cheng-Kung Road, Neihu 114, Taipei, Taiwan, ROC;(3) Department of Nuclear Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC;(4) Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; |
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| Abstract: | Extrapontine myelinolysis and pure word deafness are very uncommon disorders. Here, we report a case of a 19-year-old woman
who suffered from osmotic demyelination syndrome with coincidence of typical pure word deafness. As a consequence of rapid
correction of hyponatremia, the patient demonstrated an initial onset of cortical deafness, and then progressed to generalized
auditory agnosia, which eventually developed into confined verbal auditory agnosia (pure word deafness). Bilateral extrapontine
myelinolysis was confirmed using brain magnetic resonance imaging. This case suggests that verbal and nonverbal stimuli may
involve separate thalamocortical pathways. |
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| Keywords: | Pure word deafness Auditory agnosia Osmotic demyelination syndrome Extrapontine myelinolysis Cortical deafness |
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