Metastasis of gastric carcinoma to the thyroid and lung: a case report and review of literature |
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| Authors: | Hwa-chan Lee Fen-fen Chen Ching-chu Lo Chung-jing Wang Wei-chun Lo and Shi-ping Luh |
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| Institution: | (1) Department of Applications in Surgery of Innovative Technologies, University Medical School of Bari, Italy;(2) Department of Pathology, University Medical School of Bari, Italy;(3) Department of Radiology, University Medical School of Bari, Italy;(4) Department of Otorhinolaryngology, University Medical School of Bari, Italy |
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| Abstract: | Cancer metastasis to the thyroid is extremely rare. The more commonly reported primary sites for metastasis to the thyroid
are the kidney, breast, lung, colon, esophagus, and uterus. Thyroid metastasis from the stomach has only been reported in
three cases. Herein, we report a 71-year-old man presenting with bilateral thyroid multinodular lesions. Bilateral near-total
thyroidectomy was performed due to airway compression with related symptoms. Wedge resection of a suspicious pulmonary nodule,
detected on CT, was performed for diagnosis. Polypoid lesions in the stomach were examined by trans-scopic biopsy. Poorly
differentiated adenocarcinomas with the same histological profiles were noted at these three sites. The immunohistochemical
staining for thyroglobulin of these specimens was negative. We conclude that a new thyroid mass appearing in a patient with
present or prior malignancies should raise the concern of metastatic disease. |
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| Keywords: | Gastric carcinoma Thyroid metastasis Lung metastasis |
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