| SYNTHESIS AND PROPERTIES OF HEPARINIZED POLYMETHACRYLIC ACID |
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| 作者姓名： | Feng Pinzhen Lu Jiantao |
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| 作者单位： | Department of Chemistry，Graduate School，Academia Sinica P. O. Box 3908，Beijing 100039 |
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| 摘 要： | ＳＹＮＴＨＥＳＩＳＡＮＤＰＲＯＰＥＲＴＩＥＳＯＦＨＥＰＡＲＩＮＩＺＥＤＰＯＬＹＭＥＴＨＡＣＲＹＬＩＣＡＣＩＤ￥ＦｅｎｇＰｉｎｚｈｅｎ；ＬｕＪｉａｎｔａｏ（ＤｅｐａｒｔｍｅｎｔｏｆＣｈｅｍｉｓｔｒｙ，ＧｒａｄｕａｔｅＳｃｈｏｏｌ，ＡｃａｄｅｍｉａＳｉｎ...
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SYNTHESIS AND PROPERTIES OF HEPARINIZED POLYMETHACRYLIC ACID |
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| Feng Pinzhen, Lu Jiantao.SYNTHESIS AND PROPERTIES OF HEPARINIZED POLYMETHACRYLIC ACID[J].Journal of the Graduate School of the Chinese Academy of Sciences,1994(1). |
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| Authors: | Feng Pinzhen Lu Jiantao |
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| Abstract: | A new technique of covalent bonding of polymethacrylic acid onto heparin was described. The free radical polymerization of methacrylic acid was initiated by tetravalent ceric ion in aqueous solution and crosslinked with ethylene glycol dimethacrylate.The polymerization reaction conditions have been optimized. The antithrombogenicityof the resulting crosslinked polymer is determined.The results of recalcifiction time test (RTT) and thrombine time test (TTT) showed that the heparinized polymers are of excellent antithrombogenicity and may be interesting for biomedical applications. |
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| Keywords: | heparin heparinized polymer antithrombogenicity methacrylic acid |
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