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N—乙基沛心达对大鼠心肌细胞胞浆游离钙浓度的影响
引用本文:刘磊,杨静娴,黄彩云,邵树琴,张宝恒,范劲松.N—乙基沛心达对大鼠心肌细胞胞浆游离钙浓度的影响[J].大连大学学报,1994(1).
作者姓名:刘磊  杨静娴  黄彩云  邵树琴  张宝恒  范劲松
作者单位:大连大学医专 (刘磊,杨静娴,黄彩云,邵树琴),北京医科大学 (张宝恒),北京医科大学(范劲松)
摘    要:N—乙基沛心达对静息状态下心肌细胞胞浆)Ca~(2+)]i无显著影响,对高钾诱发心肌细胞胞浆Ca~(2+)]i升高,N—乙基沛心达2μmol/L,虽有抑制作用,但与对照组相比无显著差异(p>0.05),N—乙基沛心达10μmol/L可显著抑制大鼠心肌细胞胞浆Ca~(2+)]i升高,与对照组相比,差异显著(p<0.01)。

关 键 词:N—乙基沛心达  心肌细胞  游离钙浓度  Fura—2

The Influence of the Free [Ca~2+]i in Myocardial Cell of Rat
Liu Lei et al.The Influence of the Free [Ca~2+]i in Myocardial Cell of Rat[J].Journal of Dalian University,1994(1).
Authors:Liu Lei
Institution:Liu Lei et al
Abstract:N-ethyl perhexiline (NEP) had no obrious effect on Ca2+]i at rest. NEP 2 MMMMMMMMMMmol/L inhibited the increase in Ca2+]i induced by high K+,but no significant difference existed, compared with the control group (P)0. 05). NEP 10 umol/L had an obvious inhibitive effect on the increase in Ca2+]i induced by high K+ . A very significant difference (P<0. 01) existed, com pared with the control group.
Keywords:NEP [Ca2+]i Fura-2
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