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Ghrelin与运动的关系研究进展
引用本文:赵可伟,赵金良.Ghrelin与运动的关系研究进展[J].首都体育学院学报,2008,20(4).
作者姓名:赵可伟  赵金良
作者单位:1. 山东省体育科研中心,山东,250002
2. 山东省运动康复中心,山东,250014
摘    要:Ghrelin是生长激素促分泌素受体的内源性配体,是一种主要由胃肠分泌的含有28个氨基酸残基的短肽,它具有强烈的刺激GH分泌的功能.Ghrelin与其受体结合后可以产生广泛的生物学效应,在具有促生长激素分泌作用的同时,又具有维持能量正平衡、调节能量代谢的作用.不同的运动方式对Ghrelin水平的影响也不同,一般一次性急性运动不会导致ghrelin浓度的升高;长时间耐力性运动或者有氧健身运动,可能会导致ghrelin浓度的升高或者ghrelin对机体代谢作用的敏感性增加.本文通过查阅大量国内外文献,就Ghrelin的生物结构、分泌调控、生理功能及运动对其的影响做一综述.

关 键 词:生长激素  胰岛素  运动

On the Research Progress of the Relationship between Ghrelin and Exercise
ZHAO Ke-wei,ZHAO Jin-liang.On the Research Progress of the Relationship between Ghrelin and Exercise[J].Journal of Capital College of Physical Education,2008,20(4).
Authors:ZHAO Ke-wei  ZHAO Jin-liang
Abstract:Ghrelin is an endogenous ligand of the growth hormone secretogogue receptor,which includes 28 amino acids and is mainly produced by stomach.It has the function that stimulates GH's secretion.After combining with its receptor,Ghrelin has wide biological effects,besides its effect of stimulating GH,it can also regulate energy homeostasis.Different exercise method has different influences on ghrelin.Generally speaking,acute exercise of once won't make the level of ghrelin raise;Prolonged exercise of endurance or aerobic exercise may lead to the raise of ghrelin or the increased sensitivity of organic metabolism by Ghrelin.After a consultation of massive domestic and foreign literature,this article reviews ghrelin's molecular structure,secretion and regulation,physiological effects and the influence of exercise on ghrelin.
Keywords:Ghrelin
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