Antioxidants: Basis concepts in relation to the eye |
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| Authors: | Pradeep Venkatesh Garg Satpal Lalit Verma Tewari Hem Kumar Sheena Garg |
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| Institution: | (1) Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, 29 New Delhi |
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| Abstract: | Antioxidants are a small group of substances that protect living cells from the destructive consequences of powerful oxidizing
intermediates that can be formed from oxygen. Situations in which pro-oxidant mechanisms within the body are more active than
the antioxidant mechanisms (oxidative stress) predispose and contribute to the pathogenesis of several ailments in various
organs of the body. In the eye, pro-oxidant factors have been blamed for the causation of diseases such as age related macular
degeneration and senile cataract. The role of pro-oxidants in the genesis of certain diseases is well established however,
the effectivity of antioxidants provided to the body by dietary supplementation is inconclusive. In this article we provide
a review on the basic concepts of antioxidant-pro-oxidant interaction in relation to its effects on the eye. |
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| Keywords: | Antioxidants Pro-oxidants Oxidative stress |
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