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舍曲林联合舒必利治疗精神分裂症的临床研究
引用本文:万纯,罗琦,刘钦,吕美珍,黄美珍,廖萍.舍曲林联合舒必利治疗精神分裂症的临床研究[J].宜春学院学报,2007,29(2):115-116.
作者姓名:万纯  罗琦  刘钦  吕美珍  黄美珍  廖萍
作者单位:宜春市第三人民医院,江西,宜春,336000
摘    要:目的:探讨舍曲林合并舒必利治疗精神分裂症的疗效和安全性.方法:将60例符合CCMD-3诊断标准的精神分裂症患者随机分为研究组和对照组,研究组给予舍曲林合并舒必利治疗,对照组服用阿立哌唑,疗程8周,用PANSS、TESS评定疗效和安全性.结果:研究结束时舍曲林合并舒必利组总有效率为86.7%,阿立哌唑组总有效率83.3%,两组比较无显著性差异(P>0.05).两组不良反应少且轻.结论:采用舍曲林合并舒必利的方法治疗精神分裂症疗效可靠,安全性好,值得进一步研究.

关 键 词:精神分裂症  舍曲林  舒必利  阿立哌唑
文章编号:1671-380X(2007)02-0115-02
收稿时间:2007-03-02
修稿时间:2007-03-02

Clinical study of sertraline combined with sulpiride on treatment of schizophrenia
WAN Chun,LUO Qi,LIU Qin,LV Mei-zhen,HUANG Mei-zhen,LIAO Ping.Clinical study of sertraline combined with sulpiride on treatment of schizophrenia[J].Journal of Yichun University,2007,29(2):115-116.
Authors:WAN Chun  LUO Qi  LIU Qin  LV Mei-zhen  HUANG Mei-zhen  LIAO Ping
Abstract:Objective:To probe the efficiency and security of sertraline combined with sulpiride ontreatment of schizophrenia.Methods:60 schizophrenia patients were divided into two groups randomly,30 of Sertraline combining Slpiride group,30 of Aripiprazole group,the period of observation is 8 weeks,assessingefficiency and security of two group before treatment and 1,2,4,6,8 weeks after treating by PANSS and TESS scales.Results:Allthe subjects finished the trail.The total effective rates of twogroup were 86.7% and 83.3%,respectively, there was no significant difference between two group(P>0.05).the side effects were light.Conclusion:Sertraline combining Slpiride is effective choice on treatment of positive symptoms of schizophrenia.It can improve the life quailty of schizophrenia consumedly.
Keywords:Schizophrenia  Sertraline  Sulpiride  Aripiprazole
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