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P300/CNV事件相关电位刺激器的研制与应用
引用本文:崔岩,张一鸣,庄剑青.P300/CNV事件相关电位刺激器的研制与应用[J].实验室研究与探索,2006,25(10):1201-1204,1207.
作者姓名:崔岩  张一鸣  庄剑青
作者单位:上海中医药大学,教学实验中心,上海,201203
基金项目:致谢感谢曾兆麟教授、Dr.Toshikazu Shinba(Department of Stress Disorders Research,Toyko Institute of Psychiatry)、陈兴时、梁建华医师(上海市精神卫生研究中心电生理检查室)的帮助和指导,杨华元、顾训杰、夏锦杉、汤伟昌和高明老师(金工机械实验室)的技术支持,姜梅玲的辅助工作.
摘    要:通过研制一种特殊的刺激器,使不具备事件相关电位P300、CNV(关联性负变)检测功能的普通诱发电位仪实现P300、CNV的检测。自主设计P300/CNV刺激器的研制方案、电路和程序等,通过调试修正,完成刺激器开发。P300/CNV事件相关电位刺激器达到设计要求,能记录出较为理想的P300和CNV波形。成功研制出P300/CNV刺激器,此刺激器有一定通用性,可与诱发电位仪或生物信号处理系统配合使用;建立了适用于此刺激器的P300、CNV检测方法。此刺激器有一定实用性,可节约实验经费。目前市面上未见有类似产品,此刺激器已获中华人民共和国实用新型专利(ZL专利号:200420081185.5)。

关 键 词:P300  关联性负变  事件相关电位  刺激器  诱发电位仪
文章编号:1006-7167(2006)10-1201-05
收稿时间:2006-01-05
修稿时间:2006-01-05

Development and Application of the Stimulator for Detecting Event-Related Potentials P300/CNV
CUI Yan,ZHANG Yi-ming,ZHUANG Jian-qing.Development and Application of the Stimulator for Detecting Event-Related Potentials P300/CNV[J].Laboratory Research and Exploration,2006,25(10):1201-1204,1207.
Authors:CUI Yan  ZHANG Yi-ming  ZHUANG Jian-qing
Institution:Experiment Center for Teaching, Shanghai Univ. of Traditional Chinese Medicine, Shanghai 201203, China
Abstract:To develop a special stimulator,with which the Event-related potentials P300 and CNV(Contingent negative variation) can be elicited and recorded using an Evoked Potential Measuring System congenitally without such functions.The whole P300/CNV stimulator,including its functions,electrocircuit and program was designed.The P300/CNV stimulator could work as expected.With it,satisfying waveforms could be recorded.The P300/CNV stimulator could be applied to many kinds of evoked potential measuring systems or biological signals processing systems.Appropriate procedure for measuring P300 and CNV using this stimulator was established.
Keywords:P300  CNV  event-related potentials  stimulator  evoked potential measuring systems
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