| 苄基异喳啉生物碱在木兰亚纲等植物类群中的分布 |
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| 引用本文： | 朱敏,肖培根.苄基异喳啉生物碱在木兰亚纲等植物类群中的分布[J].中国科学院研究生院学报,1991,29(2):142-155. |
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| 作者姓名： | 朱敏 肖培根 |
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| 摘 要： | 本文详细讨论了苄基异喹啉生物碱的生源和进化趋势，化学结构类型的分布规律，植
物来源，药理作用以及它们之间的联系性。研究表明：苄基异喹啉生物碱主要存在于较原始
的木兰亚纲植物群中，阿朴菲型、双苄基异喹啉型、原小檗碱型为普遍存在的结构类型。由于
按生源路线产生的不同结构类型在植物中呈现有规律的分布，因此苄基异喹啉生物碱可作为很好的分类学指标。
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| 关 键 词： | 苄基异喹啉生物碱 木兰亚纲 化学分类 |
Distribution of Benzylisoquinolines in Magnoliidae and Other Taxa |
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| Zhu Min,Xiao Pei-Gen.Distribution of Benzylisoquinolines in Magnoliidae and Other Taxa[J].Journal of the Graduate School of the Chinese Academy of Sciences,1991,29(2):142-155. |
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| Authors: | Zhu Min Xiao Pei-Gen |
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| Abstract: | Based on the analysis of benzylisoquinoline alkaloids of 323 samples in 11 fami-
lies, 50 genera and 181 species of the Chinese flora discussed in this paper are the biogenesis,
evolution, distribution pattern and botanical sources as well as the pharmacological action of
this specific category of alkaloids.
Benzylisoquinoline alkaloids are found mainly in Magnoliidae, in which aporphines,
bisbenzylisoquinolines and protoberberines are the three major types of the alkaloids. More
specifically, aporphines appeare more concentrated in primitive woody plants such as the
Annonaceae, while bisbenzylisoquinolines are especially common in the Menispermaceae,
Thalictrum (the Ranunculaceae) and Berberis (the Berberidaceae). As to protoberberines, the
quaternary ones occur mainly in the families Ranunculaceae and Berberidaceae, whereas the
tertiary ones mainly in the relatively advanced families Menispermaceae and Papaveraceae
within Magnoliidae.
As a whole, a general rule can be drawn that the simpler the chemical structure of the
benzylisoquinolines is, the more widely they are distributed in primitive groups; more specific
ones only have a limited distribution in more advanced groups or even within one family or
one to several genera. This general pattern of distribution of benzylisoquinoline alkaloids in
plants may be of value as a taxonomic criterion for plant systematics.
Furthermore, this group of alkaloids covers the gamut of pharmacologic responses, such
as the antibacterial effect and the effect to cardiovascular and nervous systems, and
consequently the correlation between benzylisoquinoline alkaloids and their pharmacologicactivities within Magnoliidae may worthily be applied for the finding of new drugs. |
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| Keywords: | Benzylisoquinoline alkaloids Magnoliidae Chemotaxonomy |
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