| HMM在生物序列分析中的应用 |
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| 引用本文： | 陈雄峰.HMM在生物序列分析中的应用[J].闽江学院学报,2007,28(5):52-55. |
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| 作者姓名： | 陈雄峰 |
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| 作者单位： | 闽江学院计算机科学系,福建福州,350108 |
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| 摘 要： | 阐明HMM的基本理论与概念,进而总结介绍HMM应用的基本问题与算法;重点介绍并分析了可用于表示序列家族的几种HMM结构特点,并说明了利用已知家族Profile HMM构造多序列比对的方法;阐述了常用于基因发现的GHMM和目前常用于发现基因结构的HMM结构特点;最后介绍一种结合多种基因发现工具的HMM主要思想.
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| 关 键 词： | HMM 序列家族 基因发现 |
| 文章编号： | 1009-7821(2007)05-0052-04 |
| 修稿时间： | 2007年2月5日 |
HMM applications to biological sequences analyzing |
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| CHEN Xiong-feng.HMM applications to biological sequences analyzing[J].Journal of Minjiang University,2007,28(5):52-55. |
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| Authors: | CHEN Xiong-feng |
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| Abstract: | It clarifies HMM ' s foundational theories and basic concepts,and then summarizes out the basic problems and algorithms of HMM applications.It emphatically introduces and analyzes the structural characteristics of some kinds of Profile HMM for modeling sequence families,and illuminates the method of constructing the multi-sequences alignment of the family members by its known Profile HMM.It also expatiates the structural characteristics of GHMM that are frequently applied to find gene and a new kind of HMM that is frequently applied to find gene structure in current.And the main idea of a kind of HMM that can combine multiple gene finding tools is finally introduced. |
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| Keywords: | HMM sequence family gene finding |
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