| 富马酸二甲酯的合成工艺研究 |
| |
| 引用本文： | 苏秋芳,邝健钦,刘炳全,梁扬眉.富马酸二甲酯的合成工艺研究[J].茂名学院学报,1998(2). |
| |
| 作者姓名： | 苏秋芳 邝健钦 刘炳全 梁扬眉 |
| |
| 作者单位： | 广东石油化工高等专科学校石化系!茂名525000(苏秋芳，邝健钦)，广东石油化工高等专科学校!97届毕业生(刘炳全，梁扬眉) |
| |
| 摘 要： | 以马来酸酐为原料二步法合成富马酸二甲酯.首先,马来酸酐水解异构化合成富马酸,采用一种新的异构化催化剂,反应的最优条件为:15g马来酸酐和25mL水反应,加入0.1g催化剂,回流1h,产率为93.2%.然后,富马酸酯化合成富马酸二甲酯,采用对甲苯磺酸作催化剂,通过正交实验得到反应的最佳条件为:富马酸15g,对甲苯磺酸3g,醇酸摩尔比12:1,回流4h,产率为67.5%.二步法的总产率可达62.9%.
|
| 关 键 词： | 富马酸二甲酯 富马酸 马来酸酐 异构化反应 酯化反应 防霉剂 |
Study on processing condition of the synthesis of dimethyl fumarate |
| |
| Su Qiufang,Liu Bingquan,Kuang Jianqin,Liang Yangmei.Study on processing condition of the synthesis of dimethyl fumarate[J].Journal of Maoming College,1998(2). |
| |
| Authors: | Su Qiufang Liu Bingquan Kuang Jianqin Liang Yangmei |
| |
| Abstract: | Dimethl fumarate was prepared from maleic anhydride by two reaction steps. First, fumaric acid was yielded by hydrolysis and isomerization from maleic anhydride with a new catalyst. The yield of fumaric acid was 93.2% on the optimum condition of 15g of maleic anhydride,25mL of water,0. 1g of catalyst and reaction time being 1h. With the second step,dimethyl fumarate was yielded by meth - esterification from fumaric acid. The catalyst of this reaction was p - toluene sulfonic acid. The optimum reaction condition obtained by means of orthogonal test was 15g of fumaric acid,3.0g of p-toluene sulfonic acid,the mole ratio of methane alcohol to fumaric acid being 12 to 1 and reaction time being 4h. The yield of dimethyl fumarate was 67. 5% . The total yield of the two steps was 62.9%. |
| |
| Keywords: | dimethyl fumarate maleic anhydride fumaric acid isomerization esterifi cation anti-mildew agent |
| 本文献已被 CNKI 等数据库收录！ |
|
