Changes in erythrocyte membrane glycoproteins during leukaemia |
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| Authors: | Kiran Hasija |
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| Institution: | (1) Department of Biochemistry, N.S.C.B. Govt. Medical College, 482 003 Jabalpur |
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| Abstract: | Changes in erythrocyte membrane glycoproteins during, leukaemia were investigated in one hundred patients. Control group contained
normal ones. The total protein and protein bound total carbohydrates (neutral sugars) in the glycoproteins extracted from
the erythrocyte membrane showed significant reduction in total protein and protein bound total carbohydrates before radiotherapy.
However, after the radiotherapy there was further reduction in total protein by 10.41% whereas there was increase in total
carbohydrates by 9.98%. Qualitative analysis reveals that with the help of lectins one can pin point the sugars which appear
or disappear due to leukaemia. The test could be of a diagnostic value. |
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| Keywords: | RBC membrane Glycoproteins Leukaemia |
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