| 补充肌酸和抗阻训练对废用性萎缩肌肉GLUT4蛋白的影响 |
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| 引用本文： | 高淑杰.补充肌酸和抗阻训练对废用性萎缩肌肉GLUT4蛋白的影响[J].广州体育学院学报,2006,26(2):73-76. |
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| 作者姓名： | 高淑杰 |
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| 作者单位： | 沈阳体育学院生理生化教研室,辽宁,沈阳,110032 |
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| 基金项目： | 丹麦哥本哈根大学校科研和教改项目 |
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| 摘 要： | 研究了健康大学生外固定腿2周使肌肉愈接近废用性萎缩,并在固定期和恢复期10周过程中连续补充肌酸和抗阻训练,测定股外侧肌葡萄糖转运蛋白4(glucose transporter 4,GLUT4)的变化,并且测定了肌糖原、磷酸肌酸(CP)和肌酸(C)浓度。探讨补充肌酸对骨骼肌废用性萎缩后糖代谢调节机制的影响。研究结果显示:补充肌酸和抗阻训练可以提高废用性萎缩肌肉GLUT4蛋白水平,肌肉吸收葡萄糖和肌糖原合成能力增强。肌肉CP、C和C总浓度在恢复期第3周达到高水平。
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| 关 键 词： | 废用性萎缩肌肉 肌酸 GLUT4 肌糖原 |
| 文章编号： | 1007-323X(2006)02-0073-04 |
| 收稿时间： | 11 18 2005 12:00AM |
| 修稿时间： | 2005年11月18 |
Influences of Oral Creafine Supplementation and Anti- Resistance Training facilitates on GLUT4 Protein of Muscles Disuse Atrophy |
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| GAO Shu-jie.Influences of Oral Creafine Supplementation and Anti- Resistance Training facilitates on GLUT4 Protein of Muscles Disuse Atrophy[J].Journal of Guangzhou Physical Education Institute,2006,26(2):73-76. |
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| Authors: | GAO Shu-jie |
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| Institution: | Shenyang Institute of Physical Education, Shenyang 110032, China |
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| Abstract: | This study was to determine the change of GLUT4 protein,glycogen CP and C for m.vastus lateralis after the subjects were immobilized on their right legs for two weeks to disuse atrophy,supplying creatine and training for ten weeks.To discuss the effect of supplying creatine on mediated carbohydrate metabolism of skeletal muscles disuse atrophy.The results showed that content of GLUT4 protein,glucose and glycogen in muscles disuse atrophy increased after supplying creatine.After three weeks rehabilitation CP,C and total C reached the highest level. |
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| Keywords: | Muscles Disuse Atrophy: Creatine: GLUT4: Glycogen |
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