| 肌肉运动疲劳的生物标志物研究进展 |
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| 引用本文： | 赵海涛,曹庆雷,刘鑫,李小兰.肌肉运动疲劳的生物标志物研究进展[J].成都体育学院学报,2021(2):128-135. |
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| 作者姓名： | 赵海涛 曹庆雷 刘鑫 李小兰 |
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| 作者单位： | 北京科技大学体育部;北京科技大学化学与生物工程学院 |
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| 摘 要： | 肌肉疲劳是指在进行肌肉收缩活动期间产生的做功能力下降现象,在运动过程中很常见,也是限制运动员提高成绩的主要原因之一。肌肉疲劳产生生物标志物可以评估在运动期间肌肉的疲劳程度和运动对骨骼肌的影响。肌肉疲劳主要是由于能量物质耗尽,氧化应激增加,炎症反应激活等机制造成的。此外,还涉及了脱水、高氨血症、线粒体生物发生和遗传反应,文章通过梳理,把肌肉疲劳的生物标志物分为两类:一类是非侵入式的生物标志物,主要包括肌肉功率输出测量、电生理测量、心脏功能测量和摄氧量等;另一类是侵入式的生物标志物,主要包括ATP代谢、氧化应激和炎症等相关的生化指标。以期对以后运动疲劳的诊断和新的生物标志物的开发提供有价值的信息。
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| 关 键 词： | 肌肉运动 肌肉疲劳 生物标志物 |
Research Progress on Biomarkers of Muscle Exercise Fatigue |
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| ZHAO Haitao,CAO Qinglei,LIU Xin,LI Xiaolan.Research Progress on Biomarkers of Muscle Exercise Fatigue[J].Journal of Chengdu Physical Education Institute,2021(2):128-135. |
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| Authors: | ZHAO Haitao CAO Qinglei LIU Xin LI Xiaolan |
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| Institution: | (Department of Physical Education,University of Science and Technology Beijing,Beijing 100083;School of Chemistry and Biological Engineering,University of Science and Technology Beijing,Beijing 100083) |
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| Abstract: | Muscle fatigue is a phenomenon which refers to the decline in the ability of muscles to do work during muscle contraction.It is very common in the process of sports activities,and is one of the main reasons for preventing athletes from improving their performance.Muscle fatigue produces biomarkers that assess muscle fatigue during exercise and the effects of exercise on skeletal muscles.Muscle fatigue is caused by the depletion of nutrients,increased oxidative stress,and activation of inflammatory responses.In addition,it also involves dehydration,high ammonia concentration,mitochondrial biology and genetic reaction,and these reactions can be used to monitor biomarkers of sport fatigue.Through carding,the biomarkers of muscle fatigue are divided into two types:the noninvasive ones mainly including power output measurement,electrophysiological measurement,heart measurement and oxygen uptake,and the invasive ones mainly including biochemical indicators related to ATP metabolism,oxidative stress and inflammation.This paper aims to elaborate the recent research progress of biomarkers of muscle exercise fatigue and provide valuable information for the future diagnosis of exercise fatigue and the development of new biomarkers. |
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| Keywords: | muscle exercise muscle fatigue biomarkers |
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