| 长期力竭运动对大鼠卵巢ER、PR的影响 |
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| 引用本文： | 付燕,熊若虹.长期力竭运动对大鼠卵巢ER、PR的影响[J].成都体育学院学报,2007,33(6):102-104,121. |
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| 作者姓名： | 付燕 熊若虹 |
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| 作者单位： | 1. 西南民族大学,四川,成都,610041
2. 成都体育学院,四川,成都,610041 |
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| 摘 要： | 将动情周期正常的24只SD雌性大鼠(3月龄)随机分为对照组和模型组(各12只),模型组大鼠每日进行一次力竭游泳运动,直到其动情周期抑制,然后定量分析卵巢ER、PR的表达.结果:与对照组相比,力竭运动致动情周期抑制大鼠卵巢颗粒细胞和黄体细胞上ER、PR表达都明显降低.结论:长期力竭运动对卵巢ER、PR的表达具有抑制作用,卵巢颗粒细胞、黄体细胞上ER、PR的表达水平的降低可能是运动性月经失调的发生机制之一.
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| 关 键 词： | 运动性月经失调 卵巢 雌激素受体 孕激素受体 |
| 文章编号： | 1001-9154（2007）06-0102-04 |
| 收稿时间： | 2007-09-10 |
| 修稿时间： | 2007-09-10 |
Effects of Exhausting Exercises on ER and PR of Rats' Ovaries |
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| Fu Yan,Xiong Ruo-hong.Effects of Exhausting Exercises on ER and PR of Rats'''' Ovaries[J].Journal of Chengdu Physical Education Institute,2007,33(6):102-104,121. |
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| Authors: | Fu Yan Xiong Ruo-hong |
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| Institution: | Southwest University for Nationalities, Sichuan, Chengdu 610041 |
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| Abstract: | Through evaluation of the effects of long-term exhausting exercises on ER and PR of rats' ovaries,this article aims to gain more insight into mechanisms behind athletic menstrual cycle irregularities(AMI).Methods: 24(3-month-old) female Sprague-Dawley(SD) rats having normal estrus cycles are divided randomly into two groups: control group(C) and model group(M),12 rats in each group.The rats in the group M perform exhausting swimming every day till those estrous cycles are inhabited.Immuohistochemical technique and image analysis are used to assess the expression levels of ER and OR of ovaries in rats.Results: Compared with group C,both granulose cells(GCs) and lutein cells(LCs),the expression levels of ER and PR drop significantly.Conclusion: Long-term exhausting exercises block the expression of ER and PR in ovary,and the decrease in expression of ER and PR in ovary may be one of the mechanisms of AMI. |
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| Keywords: | athletic menstrual cycle irregularities ovary estrogen receptor(ER) progesterone receptor(PR) |
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