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| 急性耐力运动对大鼠不同脑区单胺类神经递质及其代谢产物的影响 | |
| 引用本文： | 宋亚军,孙勤枢,王鲁克,王宁,谢敏豪.急性耐力运动对大鼠不同脑区单胺类神经递质及其代谢产物的影响[J].北京体育大学学报,2005,28(4):484-486. |
| 作者姓名： | 宋亚军 孙勤枢 王鲁克 王宁 谢敏豪 |
| 作者单位： | 1. 山东济宁师专体育系,山东,济宁,272125 2. 山东济宁医学院化学教研室,山东,济宁,272125 3. 北京体育大学,北京,100084 |
| 摘 要： | 以大鼠端脑、间脑和脑干5-HT、DA、5HiAA和DOPAC等指标为研究对象,探讨长时间游泳对大鼠不同层次脑组织单胺类神经递质及其代谢产物的影响.研究表明:1)急性耐力运动后,脑内中枢疲劳的可能性介质--5-HT水平的提高可能发生或首先发生在某些脑区,而非全脑;其变化情况可能与运动持续时间等因素有关;2)3 h游泳运动后,间脑5-HT水平增高、DA水平显著性降低,5-HT/DA比值显著性增高;提示,间脑可能是急性耐力运动中中枢疲劳的敏感性区域;3)急性耐力运动后,大鼠端脑和脑干5-HT代谢率增高;间脑区则降低;脑内DA代谢水平在运动后普遍提高,以间脑区提高最为明显. |
| 关 键 词： | 急性耐力运动 大鼠 不同脑区 单胺类神经递质 中枢疲劳 急性耐力运动 大鼠 不同脑区 单胺 类神经递质 代谢产物 影响 Rats Region Brain Different Product Neurotransmitters Monoamine Endurance Exercise Acute 代谢水平 代谢率 区域 敏感性 |
| 文章编号： | 1007-3612(2005)04-0484-03 |
| 修稿时间： | 2003年4月29日 |
Influence of Acute Endurance Exercise on Monoamine Neurotransmitters and Its Metabolize Product in Different Brain Region of Rats |
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| SONG Ya-Jun,SUN Qin-shu,WANG Lu-ke,WANG Ning,XIE Min-hao.Influence of Acute Endurance Exercise on Monoamine Neurotransmitters and Its Metabolize Product in Different Brain Region of Rats[J].Journal of Beijing Sport University,2005,28(4):484-486. | |
| Authors: | SONG Ya-Jun SUN Qin-shu WANG Lu-ke WANG Ning XIE Min-hao |
| Abstract: | This study was designed to observe the change of 5-HT?DA?5-HIAA?DOPAC in cortex and diencephalons and brain stem of the rat immediately after acute endurance exercise and its recovery in order to explore the influence of long-time swimming on monoamine neurotransmitters and its products of metabolism in the different brain region of the rat. Several results can be shown as the followings: 1) In acute endurance exercise, 5-HT-the possible transmitter of centered fatigue, its heighten of level appeared or first appeared in certain brain region probably, but no whole brain; its change was related to the factors of the duration of exercise and so on; 2)After three-hour swimming, it was found that the 5-HT concentration increased and the level of DA reduced remarkably on the diencephalons region of the rat. The results indicate that diencephalons region was likely to be sensitive region of central fatigue; 3)After acute endurance exercise, metabolize rate of 5-HT increased in cortex and brain stem of the rat, but the rat of metabolism rate of DA widespread increased in the whole brain after exercises, among them, the raise of DA concentration was most clear in diencephalons of the rat. |
| Keywords: | acute endurance exercise rat different brain region monoamine neurotransmitter central fatigue |
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