| 运动性血红蛋白低下大鼠红细胞膜组分和功能的变化 |
| |
| 引用本文： | 潘孝贵,徐宏伟.运动性血红蛋白低下大鼠红细胞膜组分和功能的变化[J].北京体育大学学报,2010(3). |
| |
| 作者姓名： | 潘孝贵 徐宏伟 |
| |
| 作者单位： | 湖州师范学院体育学院; |
| |
| 基金项目： | 安徽省教育厅青年教师科研资助项目(2004jql904);;湖州师范学院科研创新团队计划资助(XK25002) |
| |
| 摘 要： | 目的:探讨运动性血红蛋白低下时红细胞膜组分和功能变化的规律。对象与方法:将雄性SD大鼠60只,随机分为3组:对照组、跑台运动组、负重游泳组。经跑台或负重游泳训练后,将血红蛋白持续下降的大鼠纳入运动性血红蛋白低下组。取血,制备红细胞悬液,测定红细胞膜磷脂成分、带3蛋白含量、磷脂酰丝氨酸外翻率、阴离子转运功能、葡萄糖转运功能、钠钾ATP酶活性及变形能力。结果:与对照组比较,运动性血红蛋白低下组大鼠磷脂中脑磷脂和卵磷脂丢失较多(p<0.01),带3蛋白含量显著升高。同时,磷脂酰丝氨酸外翻率、红细胞滤过分数显著上升(p<0.01),阴离子转运功能、葡萄糖转运能力、钠钾ATP酶活性均显著下降(p<0.05)。结论:长时间激烈运动通过影响红细胞膜组分和功能,导致红细胞损伤和老化,清除标记增多,膜流变性下降,变形能力减弱,造成红细胞溶血和/或清除增多,发生运动性血红蛋白低下。
|
| 关 键 词： | 运动性血红蛋白低下 红细胞膜 磷脂 膜蛋白 |
Alteration of Structure and Function of Red Cell Membrane in Rats with Sports Hypochrosis |
| |
| PAN Xiao-gui,XU Hong-wei.Alteration of Structure and Function of Red Cell Membrane in Rats with Sports Hypochrosis[J].Journal of Beijing Sport University,2010(3). |
| |
| Authors: | PAN Xiao-gui XU Hong-wei |
| |
| Institution: | Department of Physical Education;Huzhou normal University;Huzhou 313000;Zhejiang China |
| |
| Abstract: | The aim of this paper was to elucidate the alterations of red cell membrane that occur in rats following treadmill running or forced swimming.13 of 20 rats in treadmill training group and 10 of 20 rats in forced swimming group,whose Hb content decreased insistently,were subjected to sports hypochrosis group.The profile of phospholipids and band 3 protein of erythrocyte membrane were investigated,and the eversion rate of phosphatidylserine,transport function of band 3 protein,glucose transporter protein,and ... |
| |
| Keywords: | sports hypochrosis red cell membrane membrane phospholipids membrane proteins |
| 本文献已被 CNKI 等数据库收录！ |
|
