| 支链氨基酸对运动力竭大鼠心肌损伤的保护作用 |
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| 引用本文： | 张 钧,夏云健,黄叔怀.支链氨基酸对运动力竭大鼠心肌损伤的保护作用[J].天津体育学院学报,1999,14(3):30-33. |
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| 作者姓名： | 张 钧 夏云健 黄叔怀 |
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| 作者单位： | 扬州大学体育学院, 225002 |
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| 摘 要： | 以大鼠力竭运动为模型,研究了支链氨基酸(BCAA)对血清和心肌中乳酸脱氢酶(LDH),谷草转氨酶(GOT),肌酸激酶(CK),α-羟丁酸脱氢酶(α-HBDH)等酶的活性以及心肌中Ca2 ,Mg2 含量的影响。结果发现:力竭运动可造成大鼠血清和心肌中LDH,GOT,CK,α-HBDH 等酶的活性显著升高,心肌中Ca2 含量也显著升高,Mg2 含量显著下降。补充BCAA 可使大鼠力竭运动后血清和心肌中LDH,GOT,CK,α-HBDH 等酶的活性显著降低,心肌中Ca2 含量显著下降。提示,BCAA 可抑制大鼠力竭运动后血清和心肌中LDH,GOT,CK,α-HBDH 等酶的活力显著升高和心肌中钙超载。说明BCAA 有减少力竭运动后心肌损伤和维持心肌正常功能的作用。
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| 关 键 词： | 支链氨基酸 力竭运动 大鼠 心肌损伤 |
PROTECTIVE ACTION OF BRANCHED-CHAIN AMINO ACID AGAINST EXERCISE-INDU CED MYOCARDIAL DAMAGE IN RATS |
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| ZHANG Jun,XIA Yun-jian and HUANG Shu-huai.PROTECTIVE ACTION OF BRANCHED-CHAIN AMINO ACID AGAINST EXERCISE-INDU CED MYOCARDIAL DAMAGE IN RATS[J].Journal of Tianjin Institute of Physical Education,1999,14(3):30-33. |
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| Authors: | ZHANG Jun XIA Yun-jian and HUANG Shu-huai |
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| Institution: | ZHANG Jun XIA Yun jian HUANG Shu huai |
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| Abstract: | Using the model of exhaustive exercise, the present study researches effects of branched-chain amino acid (BCAA ) on activities of lactate dehydro genase(LDH),glutamic-oxaloacetic amino transfer ase(GOT),creatine kinase (CK) and A-hydrobutyric dehydro genase (AHBDH) in serum and myocardium as well as contents of myocardial Ca2+ and Mg 2+ in rats. Results are followings: activities of LDH, GOT , CK and A-HBDH in serum and myocardium increase significantly in rats after exhaustive exercise; the content of myocardial Ca2+ increases significantly while that of myocardial Mg 2+ decreases significantly in rats after exhaustive exercise; the supplement of BCAA raises activities of LDH, GOT , CK and A-HBDH in serum and myocardium as well as the content of myocardial Ca2+ in rats after exhaustive exercise. The article suggests the protective action of BCAA against exercise-induced myocardial damage in rats. |
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| Keywords: | BCAA exhaustive exercise rat myocardial damage |
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