| 长期运动训练对老年小鼠心肌线粒体抗氧化能力的影响 |
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| 引用本文： | 卢 健,陈彩珍,许豪文,许永刚,赖荣兴.长期运动训练对老年小鼠心肌线粒体抗氧化能力的影响[J].天津体育学院学报,1999,14(2):23-25. |
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| 作者姓名： | 卢 健 陈彩珍 许豪文 许永刚 赖荣兴 |
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| 作者单位： | 广州体育学院 |
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| 摘 要： | 采用小鼠跑转笼运动方式，研究了从５月龄开始为期８个月的运动训练对小鼠心肌抗氧化应激能力的影响。结果发现，随年龄的增长心肌线粒体ＭｎＳＯＤ和ＧＳＨ－ｐｘ活性有升高趋势，而运动训练组小鼠心肌线粒体ＭｎＳＯＤ和ＧＳＨ－ｐｘ活性又显著高于对照组。这表明，衰老过程中心肌线粒体自由基的产生增加，从而诱导抗氧化酶产生增加。而长期有规律的适量运动训练能适量增强机体抗氧化能力，抑制脂质过氧化。
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| 关 键 词： | 运动训练 老年小鼠 心肌线粒体 氧化与抗氧化 |
EFFECTS OF PROLONGED PHYSICAL TRAINING ON A NTIOXIDATION IN AGED MICE MYOCARDIAL MITOCHON DRIA |
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| LU Jian,CHEN Cai-zhen,XU Hao-wen,XU Yong-gang and LAI Rong -xing.EFFECTS OF PROLONGED PHYSICAL TRAINING ON A NTIOXIDATION IN AGED MICE MYOCARDIAL MITOCHON DRIA[J].Journal of Tianjin Institute of Physical Education,1999,14(2):23-25. |
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| Authors: | LU Jian CHEN Cai-zhen XU Hao-wen XU Yong-gang and LAI Rong -xing |
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| Institution: | Guangzhou Institute of Physical Education, Guangzhou 510076, China |
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| Abstract: | Using the exercise mode of running wheel, the present study observes effects of eight month physical training on antioxidation in aged mice myocardium which initiated physical training at 5 months of age . Results show that activities of myocardial mitochondrial MnSOD and GSH-pxin the physical training group are significantly higher than those in the control group.The paper indicates that free radicals induce the increase of antioxidant enzymes in my cardial mitochondria during the aging process and prolonged regular physical training can increase antioxidatiion moderately as well as inhibit the occurrence of lipid peroxide. |
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