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长时间力竭游泳对大鼠心肌线粒体膜和基质游离钙的影响
引用本文:毛丽娟,许豪文.长时间力竭游泳对大鼠心肌线粒体膜和基质游离钙的影响[J].体育科学,2001,21(1):55-57.
作者姓名:毛丽娟  许豪文
作者单位:华东师范大学 体育系,
摘    要:本实验以力竭游泳(300±50min)的大鼠为运动疲劳模型,观察了大鼠心肌线粒体的巯基(-SH)、还原型谷胱苷肽(GSH)、磷脂酶A

关 键 词:力竭游泳  心肌线粒体  磷脂酶A2  游离钙  谷胱苷肽  活性氧
文章编号:1000-677X(2001)01-0055-03
修稿时间:2000年8月30日

Effects of Prolonged Exhaustive Swimming on Myocardial Mitochondria Membrane and Free Calcium of Matrix in Rat
MAO Li,juan et al.Effects of Prolonged Exhaustive Swimming on Myocardial Mitochondria Membrane and Free Calcium of Matrix in Rat[J].China Sport Science,2001,21(1):55-57.
Authors:MAO Li  juan
Abstract:Rats on acute exhaustive swimming were used as experimental models. Sulfhydryl( SH), Glutathione(GSH), phosphlipase A 2(PLA 2) and free Calcium(Ca 2 ) of myocardial mitochondrion after exhaustive exercise in rats were investigated. The results showed that SH, GSH and Ca 2 content in myocardial mitochondrion after exhaustive exercise were significantly degraded than that of the resting group. According to the results, the relationship among the oxidant reduction reaction of exercise induced reactive oxygen species, the changes of myocardial mitochondria membrane structure and the fee calcium of matrix was discussed. It is suggested that increasing of PLA 2 activity might be a key parameter of fatigue after prolonged exhaustive exercise. By means of further observation the molecules mechanism of prolonged exercise induced fatigue appearance could be further deeply understood.
Keywords:fatigue  myocardium  mitochondria  phospholipid  calcium  glutathione
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