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β-受体阻断剂对心脏康复跑台运动时机能、生理、临床和感觉反应的影响
引用本文:刘洵,Brodie D A,任丽伟,Bundred P E.β-受体阻断剂对心脏康复跑台运动时机能、生理、临床和感觉反应的影响[J].体育科学,2006,26(9):28-30,33.
作者姓名:刘洵  Brodie D A  任丽伟  Bundred P E
作者单位:1. 天津体育学院,运动人体科学系,天津,300381
2. Research Centre for Health Studies, Buckinghamshire Chilterns University, Buckinghamshire HP8 4AD, UK
3. Department of Primary Care, University of Liverpool,Liverpool L69 3BX,UK
基金项目:天津市高等学校科技发展基金
摘    要:目的:测试服用和未服用β-受体阻断剂的心梗后患者(PMIP)在跑台运动中其功能、生理、临床及自我感觉方面的反应。方法:46名服用β-受体阻断剂的男性PMIP和55名未服用β-受体阻断剂的男性PMIP进行递增负荷运动实验,其间记录每级负荷时的摄氧量(VO2)、心率(HR)、血压和自我用力感觉(RPE),并持续监测12导联心电图(ECG)。结果:服用β-受体阻断荆的患者其安静时和运动中的HR、最大心率百分比(%HRmax)及心率血压乘积(RPP)显著低于未服用β-受体阻断剂的患者(P〈0.01)。运动中,服用β-受体阻断剂的患者有59%能够完成改良布鲁斯跑台方案的第Ⅳ级运动,而在未服用β-受体阻断剂的患者中仅有49%能完成这一负荷。两组在运动中各级别VO2、RPE及ST段下移无显著性差异。结论:由β受体阻断剂所致的HR降低并没有直接地影响到氧利用和代谢机能。

关 键 词:β-受体阻断剂  心脏  康复  临床  影响
文章编号:1000-677X(2006)09-0028-03
收稿时间:2006-05-26
修稿时间:2006-05-262006-06-20

Effects of Beta-blockade on Functional,Physiological ,Clinical and Perceptual Response to Treadmill Exercise in Cardiac Rehabilitation
LIU Xun,Brodie D A,REN Li-wei,Bundred P E.Effects of Beta-blockade on Functional,Physiological ,Clinical and Perceptual Response to Treadmill Exercise in Cardiac Rehabilitation[J].China Sport Science,2006,26(9):28-30,33.
Authors:LIU Xun  Brodie D A  REN Li-wei  Bundred P E
Institution:1. Department of Human Movement Science, Tianjin University of Sport, Tianjin 300381, China; 2. Research Centre for Health Studies, Buckinghamshire Chilterns University, Buckinghamshire HP8 4AD, UK; 3, Department of Primary Care, University of Liverpool, Liverpool L69 3BX,UK,
Abstract:The purpose of this study was to examine the functional,physiological,clinical and perceptual responses during treadmill exercise of post myocardial infarction patients(PMIP) with and without beta-blockade therapy.Forty-six male recent PMIP with beta blockade therapy and 55 male recent PMIP without beta blockade therapy performed a graded exercise test.During which,the oxygen uptake(O_2),heart rate(HR),blood pressure and ratings of perceived exertion (RPE) were recorded,and a 12 lead electrocardiogram(ECG) was monitored continuously.The result showed that patients using beta-blockade had a significantly lower(P<0.01) HR,percentage of maximum heart rate(%HRmax) and rate-pressure product(RPP) both at rest and during exercise.During exercise 59% of patients using beta-blockade completed stage IV of the modified Bruce treadmill protocol,whereas in the non-blockade group,only 49% of the patients achieved this stage.There was a non-significant difference between the two groups in terms of O_2,RPE and ST segment depression at any stage during exercise test.Conclusion:The reduction in HR as a result of beta blockade does not impact directly on all other aspects of metabolism and oxygen utilization.
Keywords:beta-blockade post myocardial infarction patients exercise-based cardiac rehabilitation
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