|
|||||
|
|
| 骨骼肌细胞骨架蛋白和小分子热休克蛋白研究进展 | |
| 引用本文： | 高前进,马新东,谢丽荣,许凤莲,王瑞元.骨骼肌细胞骨架蛋白和小分子热休克蛋白研究进展[J].体育科学,2005,25(3):70-74. |
| 作者姓名： | 高前进 马新东 谢丽荣 许凤莲 王瑞元 |
| 作者单位： | 1. 石家庄学院,体育系,河北,石家庄,050035 2. 清华大学,体育部,北京,100084 3. 石家庄第二中学,河北,石家庄,050000 4. 北京体育大学,北京,100084 |
| 摘 要： | 细胞骨架蛋白是骨骼肌细胞具有重要功能的结构。中间丝蛋白desmin和膜骨架蛋白dystrophin是骨骼肌中重要的骨架蛋白 ,是研究运动性骨骼肌细胞微损伤的敏感指标。综述了近年关于骨骼肌细胞骨架蛋白和与细胞骨架蛋白损伤相关联的热休克蛋白的研究。热休克蛋白是有机体内源性保护蛋白 ,在应激条件下 ,这些蛋白合成增多 ,建立了独特的防御系统来维持细胞内蛋白的稳定 ,保证细胞的生存 ;小热休克蛋白对维持骨骼肌细胞骨架结构稳定和帮助其在损伤修复方面起关键作用。 |
| 关 键 词： | 骨骼肌 细胞骨架蛋白 小分子 热体克蛋白 аB-晶状体蛋白 |
| 文章编号： | 1000-677X(2005)03-0070-05 |
Research Development of Skeletal Muscle Cytoskeleton and Small Heat Shock Proteins |
|
| GAO Qian-jin,MA Xin-dong,XIE Li-rong,XU Feng-lian,WANG Rui-yuan.Research Development of Skeletal Muscle Cytoskeleton and Small Heat Shock Proteins[J].China Sport Science,2005,25(3):70-74. | |
| Authors: | GAO Qian-jin MA Xin-dong XIE Li-rong XU Feng-lian WANG Rui-yuan |
| Institution: | GAO Qian-jin1,MA Xin-dong2,XIE Li-rong3,XU Feng-lian1,WANG Rui-yuan 41.Department of Physical Education of Shijiazhuang University,Shijiazhuang 0500 35,China,2.The Department of Physical Education of Qinghua University,Beijing 100084,China,3.The Second Meddle School of Shijiazhuang,Shijiazhuang 050000,Ch ina,4.Beijing Sports University,Beijing 100084,China. |
| Abstract: | Cytoskeleton is an important structure of skeletal m uscle cells.Intermediate filament desmin and membrane cytoskeleton dystrophin ar e important cytoskeleton which are sensitive hallmark in the study of exercise i nduce muscle damage.This paper summarizes the result about cytoskeleton and smal l heat shock protein,heat shock proteins are the stress protein that promote cel l survival during physiological stress.Upregulation of synthesis of a number of these proteins upon environmental stress establish a unique defense system to ma intain cellular protein homeostasis and ensure survival of the cell.Small heat s hock protein is thought to play a role in protect against cytoskeletal disruptio n and aid to repair the damaged muscle. |
| Keywords: | skeletal muscle cytoskeleton smal l molecule heat shock protein B-crystallin |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |