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枸杞、运动对大鼠肾脏凋亡蛋白Bcl-2、Bax表达自由基代谢的影响
引用本文:郭朝霞,汪君民.枸杞、运动对大鼠肾脏凋亡蛋白Bcl-2、Bax表达自由基代谢的影响[J].福建体育科技,2011,30(2):32-34.
作者姓名:郭朝霞  汪君民
作者单位:福建体育职业技术学院运动系;
摘    要:目的:探讨枸杞与细胞凋亡以及枸杞、自由基和细胞凋亡之间的关系,旨在为运动训练提供一个有效的辅助手段,为中药在运动训练和健身中的广泛而深入的应用提供依据.方法:选用40只Wistar大鼠随机分为对照组、训练组和药物组,递增负荷游泳运动.测调亡蛋白用免组化,显示肾脏组织中凋亡蛋白Bcl-2和Bax的分布和表达特点,用计算机...

关 键 词:枸杞  肾脏  细胞凋亡  Bcl-2  Bax  自由基

The Effeetion of Lycium Barbarum and Exercise on the Rats' Kidney Apoptosis Protein Bcl-2 and Bax Expression and Free Radical
Guo Zhao-xia et al.The Effeetion of Lycium Barbarum and Exercise on the Rats' Kidney Apoptosis Protein Bcl-2 and Bax Expression and Free Radical[J].Fujian Sports Science and Technology,2011,30(2):32-34.
Authors:Guo Zhao-xia
Institution:Guo Zhao-xia et al(Fujian Sports Vocational Collgeg,No151 Fufei Road,Fuzhou,350003,China)
Abstract:Introduction:The author discusses the relation between the Lycium barbarum and apoptosis,among the Lycium barbarum andfree radical.Furthermore,the author would like to provide an effective auxiliary method to strengthen exercise capability and an evidence to adopt Chinese medicine widely in the training and physical exercising.Method:40 healthy 8-week-old female Wistar rats which weighed 220±23.19g each were divided into three teams of CONTROL、SPORT and MADICINE-TAKEN randomly.They were trained to take incremental swimming.The location and expression feature of apoptosis protein Bcl-2 and Bax were showed with immunohistochemistry.Finally,Bcl-2 and Bax in the rats’ kidneys were analyzed with the computer image collection and analysis technology to demonstrate the variety of Bcl-2 and Bax protein expression in different teams.Conclusion:Taking Lycium barbarum and training enhances the kidney’s capacity of anti-oxidation and anti-free radical.The Lycium barbarum relieves whose antagonism Bcl-2 coming the mechanism expressing mainly by reducing the apoptosis protein Bax restrain the body’s cell apoptosis much more obviously.Furthermore,taking training and Lycium barbarum can restrain cell apoptosis by adjust the ratio of Bcl-2 and Bax.
Keywords:Lycium Barbarum  Kidney  Apoptosis Bcl-2  Bax  Free Radical  
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