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| 带蒂大纲膜包肾防治肾小球硬化的实验研究 | |
| 引用本文： | 董兴刚,安增梅,杨海春,周江华,殷祥雷,顾建新.带蒂大纲膜包肾防治肾小球硬化的实验研究[J].科技通报,2001,17(4):73-75. |
| 作者姓名： | 董兴刚 安增梅 杨海春 周江华 殷祥雷 顾建新 |
| 作者单位： | 1. 上海市第二人民医院肾内科, 2. 复旦大学医学院华山医院肾内科, 3. 复旦大学医学院基因研究中心, |
| 基金项目： | !市“跨世纪人才”基金资助项目(199840 9) |
| 摘 要： | 为探讨带蒂大纲膜包肾术防治肾小球硬化的作用，采用单侧肾切除加二次注射阿霉素剂备的肾小球硬化动物模型，观察带蒂大纲膜包肾对肾脏的作用，结果表明，带蒂大纲膜包肾可降低血胆固醇、甘油三脂、尿蛋白排泄、肾小球球囊粘连减轻，血尿素氮有下降趋势，说明带蒂大纲膜包肾术对肾小球硬化大鼠的肾脏损伤有保护作用。 |
| 关 键 词： | 带蒂大纲膜包肾 肾小球硬化 蛋白尿 治疗 |
| 文章编号： | 1001-7119(2001)04-0073-03 |
| 修稿时间： | 2000年5月26日 |
The Effects of Pedicled Omental Transposition on Rats with Glomerulosclerosis |
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| DONG Xing-gang,AN Zeng-mei,YANG Hai-Chun,Zhou Jianghua,Yin Xianglei,Gu Jianxin.The Effects of Pedicled Omental Transposition on Rats with Glomerulosclerosis[J].Bulletin of Science and Technology,2001,17(4):73-75. | |
| Authors: | DONG Xing-gang AN Zeng-mei YANG Hai-Chun Zhou Jianghua Yin Xianglei Gu Jianxin |
| Institution: | DONG Xing gang 1,AN Zeng mei 1,YANG Hai chun 2 et al |
| Abstract: | To investigate the protective effects of pedicled omental transposition on the kidney with glomerulosclerosis.Uninephrectomized rats were divided into two groups.Normal rats were put in the blank control group,glomerulosclerosis rats by adriamycin were divided into glomerulosclerosis group and pedicled omental transposition group.Serum lipids,urea and urinary protein were assayed. Renal histological examination was also performed. Results showed that pedicled omental transposition could not only reduced the serum levels of total cholesterol and triglyceride, but also decrease the accumulation of extracellular matrix ( P <0.05).Conclusions pedicled omental transposition has the effect of attenuating renal damage in rats with glomerulosclerosis. |
| Keywords: | pedicled omental transposition glomerulosclerosis proteinuria |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |