| 豚鼠、大鼠气道反应性及药物作用的计算机测量系统 |
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| 引用本文： | 朱朝阳,曾玲晖,杨胜天,魏尔清.豚鼠、大鼠气道反应性及药物作用的计算机测量系统[J].科技通报,2000,16(2):81-85. |
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| 作者姓名： | 朱朝阳 曾玲晖 杨胜天 魏尔清 |
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| 作者单位： | 浙江大学医学院药理学教研室,神经生物学实验室,浙江,杭州,310031 |
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| 基金项目： | 国家自然科学基金!资助项目 (39770 865 |
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| 摘 要： | 在豚鼠和大鼠的气道反应性测定中，采用计算机代替记录仪记录呼吸波形，并用自行开发的ＺＵＮＬ－Ａｉｒｗａｙ１．０软件代替手工方法计算呼吸频率和通气量，结果在豚鼠和大鼠的气道反应性实验和哮喘及平喘药物的动物实验研究中与以前的结果是一致的。采用计算机进行动物气道反应性测定，除方便和省时外，也较为准确，客观，实用性较强。
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| 关 键 词： | 气道反应性 计算机测量系统 药物作用 动物实验 |
| 文章编号： | 1001-7119(2000)02-0081-05 |
| 修稿时间： | 1998-12-29 |
Computer-assisted Measurement for Airway Responsiveness and Drug Action in Conscious Guinea-pig and Sedated Rats |
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| ZHU Chao-yang,ZENG Ling-hui,YANG Sheng-tian,WEI Er-qing.Computer-assisted Measurement for Airway Responsiveness and Drug Action in Conscious Guinea-pig and Sedated Rats[J].Bulletin of Science and Technology,2000,16(2):81-85. |
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| Authors: | ZHU Chao-yang ZENG Ling-hui YANG Sheng-tian WEI Er-qing |
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| Abstract: | The routine recording device was replaced by a computer assisted measuring system which was run on a self designed software ZUNL Airway 1.0 to record the respiratory rate (RR) and ventilation volume in conscious guinea pig and diazepam sedated or conscious rats. The result showed that the computer assisted measuring system was op practical value as well as accurate and efficient. |
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| Keywords: | airway responsiveness computer assisted measuring system guinea pig rat |
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