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Cardiac troponin-T and CK-MB (mass) levels in cardiac and non cardiac disease
Authors:G Chinnapu Reddy  G Kusumanjali  A H R Sharada  Pragna Rao
Institution:(1) Kamineni Institute of Medical Sciences, Narketpally, 508 254 Nalgonda District, Andhra Pradesh;(2) Kamineni Hospitals Ltd., L.B. Nagar, 500 068 Hyderabad, India
Abstract:Serum cardiac troponin T (cTnT) and CKMB (mass) were analysed in three groups of patients. The first group (n=32) were patients with acute coronary syndromes including myocardial infarction. The second group (n=35)were patients with hypertension. The third group (n=24) were patients who had succumbed to non cardiac diseases. In all 3 groups, cardiac troponin T was elevated when compared with controls (p<0.001). However, CKMB elevation was not significant in all groups. CKMB levels correlated well with troponin T levels only when CKMB was greater than 50 ng/ml (r=1.00). Small elevations of troponin T identifies minimal cardiac necrosis and patients can benefit from early invasive therapy.
Keywords:Troponin-T  CK-MB (mass)  hypertension  acute coronary syndromes
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