Studies on the effect of monosodium glutamate (MSG) administration on the activity of xanthine oxidase, superoxide dismutase and catalase in hepatic tissue of adult male mice |
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Authors: | Kuldip Singh P Ahluwalia |
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Institution: | (1) Department of Biochemistry, Panjab University, 160014 Chandigarh, India |
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Abstract: | Subcutaneous administration of monosodium glutamate (MSG), to normal adult male mice, for six consecutive days at dose levels
of 4 and 8 mg/g body weight, significantly increased the level of free radical initiating enzyme, xanthine oxidase, whereas
the activity of free radical scavenging enzymes, like catalase and superoxide dismutase was significantly decreased in hepatic
tissue. These observations suggested that ingestion of MSG at dose level of 4 mg/g body weight and above, induced oxidative
stress in the hepatic tissue of adult male mice. |
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Keywords: | Monosodium glutamate (MSG) Xanthine oxidase (XOD) Superoxide dismutase (SOD) Catalase (CAT) and Oxidative stress |
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