Microscopic haematuria as an occult filarial infection in bhubaneshwar an endemic area for bancroftian filariasis |
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| Authors: | R Alli B Bhunia G P Chhotray M V R Reddy B C Harinath |
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| Institution: | (1) Dept. of Biochemistry & J. B. Tropical Disease Research Centre, MGIMS, 442 102 Sevagram (Wardha), India;(2) Dept. of Pathology, Regional Medical Research Centre (Indian Council of Medical Research), Chandrasekhapur, 751 016 Bhubaneshwar, India |
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| Abstract: | Sera samples of 7 microscopic haematuria cases collected before and after treatment with Diethylcarbamazine citrate, (DEC),
9 microfilaraemic cases and 19 endemic normal individuals were analysed for filarial antigen and IgG antibody levels. Filarial
antigen was detected in 5 of the 7 microscopic haematuria cases, of which 3 turned negative for antigen after treatment with
DEC. While none of the 7 haematuria cases were positive for filarial IgG antibodies, before the DEC treatment, all of them
turned positive after DEC treatment. The sensitivity and specificity values(to detect mf +ve cases) were 89% and 90% respectively
for the detection of filarial antigen and 78% and 95% respectively for the detection of filarial IgG antibodies. |
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| Keywords: | Filariasis Wuchereria bancrofti Brugia malayi microscopic haematuria |
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