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A biochemical study on the effect of Riboflavin on cataractous rat lenses. II Proteins and Glutathione
Authors:Rita R Vani  U M Rawal
Institution:1. Ocular Biochemistry Lab., Dept. of Zoology, School of Sciences, Gujarat University, 380 009, Ahmedabad
Abstract:Proteins and glutathione (GSH) levels were estimated in the experimental groups. Levels of both proteins and glutathione in the control and the treated groups were found to be significantly decreased compared to the normal group. The results show that supplementation of riboflavin has beneficial effect by alleviating the oxidant injuries to GSH and proteins, which are involved in the maintenance of transparency and protection of thiol groups of the lens. Thus, riboflavin has an active role in the lens metabolism and has a potential to improve the metabolic activity of the cataractous lenses.
Keywords:lens  cataract  riboflavin  proteins and glutathione
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