| 方波伏安法测定药物中丝裂霉素的含量 |
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| 引用本文： | 徐茂田,朱效华.方波伏安法测定药物中丝裂霉素的含量[J].商丘师范学院学报,2012(3):56-58. |
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| 作者姓名： | 徐茂田 朱效华 |
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| 作者单位： | 商丘师范学院化学化工学院;华南师范大学化学与环境学院 |
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| 基金项目： | 国家自然科学基金资助项目(21175091) |
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| 摘 要： | 在磷酸盐缓冲溶液(pH 7.4)中,利用循环伏安法研究了丝裂霉素的电化学行为.结果显示,丝裂霉素在玻碳电极上出现一对氧化还原峰,其中Epa=-0.520 V,Epc=-0.556 V.方波伏安峰电流与丝裂霉素的浓度在5×10-6～1.0×10-4mol/L之间呈良好的线性关系,检出限为1.5×10-6mol/L,可用于样品的测定.
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| 关 键 词： | 丝裂霉素 方波伏安法 测定 |
Determination of mitomycin by square wave voltammetry |
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| XU Maotian,ZHU Xiaohua.Determination of mitomycin by square wave voltammetry[J].Journal of Shangqiu Teachers College,2012(3):56-58. |
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| Authors: | XU Maotian ZHU Xiaohua |
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| Institution: | 1.School of Chemistry and Chemical Engineering,Shangqiu Normal University,Shangqiu 476000,China; 2.School of Chemistry and Environment,South China Normal University,Guangzhou 510631,China) |
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| Abstract: | The electrochemical behaviors of mitomycin were studied by cyclic voltammetry in PBS solution(pH 7.4).At GC electrodes,the mitomycin produces a sensitive redox peak.The oxidation and reduction peak potential are-0.520 and-0.566 V,respectively.The square wave peak currents are proportional to the concentrations of mitomycin in the range of 5×10-6-1.0×10-4 mol/L with a detection limit of 1.5×10-6 mol/L.The proposed method could be applied to the determination of mitomycin in pharmaceuticals. |
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| Keywords: | mitomycin square wave voltammetry determination |
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