| 核医学肝胆显像剂IODIDA的合成研究 |
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| 引用本文： | 苏秋芳.核医学肝胆显像剂IODIDA的合成研究[J].茂名学院学报,1995(2). |
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| 作者姓名： | 苏秋芳 |
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| 摘 要： | 为合成肝胆显像剂IODIDA,以活泼芳香胺为原料,经改进的直接碘化法,选择性碘代芳香胺。在吡啶与醋酐存在下,用相应的碘代芳香胺与氮三乙酸反应,可得所需产物,产率较好。
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| 关 键 词： | 锝放射性药物 肝胆显像剂 亚氨二乙酸衍生物 |
Research On The Synthesis of The Hepatobiliary Imaging Agent lodioa |
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| Su Qinfang.Research On The Synthesis of The Hepatobiliary Imaging Agent lodioa[J].Journal of Maoming College,1995(2). |
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| Authors: | Su Qinfang |
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| Abstract: | Thin paper reporte the synthesis of N - (2,6-diethyl - 3 -iodo - phenylcarbamoyImethyl)iminodiaceti-cacid(10DIDA) which in superior to the other hepatobiliary imaging agent at preaent. The key atep ia the aelecting iodi-nation and amine group protection of 2.6 -diethyl -aniline. When 2.6-diethyl - 3-iodo-aniline reacted with nitril-triacetic arid in the prenence of acetic anhydride and andydiroua pyridine , the IODIDA ia obtained in good yield. |
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| Keywords: | mTc radiopharmaceutical hepatobiliary imaging agent iminodiacetic acid derivatives |
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