| 硫普罗宁治疗急性戊型肝炎的疗效观察 |
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| 引用本文： | 高玉芳.硫普罗宁治疗急性戊型肝炎的疗效观察[J].襄樊学院学报,2014(5):87-88. |
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| 作者姓名： | 高玉芳 |
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| 作者单位： | 湖北文理学院校医院; |
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| 摘 要： | 目的：观察硫普罗宁治疗急性戊型肝炎的临床疗效和安全性.方法：急性戊型肝炎患者65例，随机分为治疗组33例，应用硫普罗宁0.2g加入5%葡萄糖注射液200ml中静脉滴注，每日1次；对照组32例，常规应用护肝药物如肌苷注射液等静脉滴注，疗程均为2周.观察治疗前后两组的症状、体征及肝功能情况.结果：硫普罗宁治疗后患者临床症状和肝功能均有显著改善.两组比较发现，ALT 好转情况、显效率和总有效率差异均有显著性（P＜0.05）.结论：硫普罗宁治疗急性戊型肝炎有较好疗效，且未见不良反应，用药安全.
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| 关 键 词： | 急性戊型肝炎 硫普罗宁 肝功能指标 |
Clinical Evaluation on the Effect of Tiopronin in Acute Hepatitis E |
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| GAO Yufang.Clinical Evaluation on the Effect of Tiopronin in Acute Hepatitis E[J].Journal of Xiangfan University,2014(5):87-88. |
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| Authors: | GAO Yufang |
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| Institution: | GAO Yufang (The school Hospital, Hubei University of Arts and Science, Xiangyang 441053, China) |
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| Abstract: | Objective To evaluate the treatment efficacy and safety of tiopionin for acute hepatitis E.Methods Sixty-five patients with acute hepatitis E were divided randomly into observation group （33 cases） and control group （ 32 cases）.The observation group was treated with tiopionin for two weeks,with 0.2g tiopronin added to 200ml 5%glucose injection for intravenous drip, the control group was treated with conventional drugs such as inosine for two weeks.Then clinical effect in each group was observed.Results The clinical effects of the observation group was higher than that of the control group;the situation of ALT, total effective rate are obvious（P＆lt;0.05）.Conclusion Tiopronin is worthy of clinical application to treat acute hepatitis E because it possesses the advantages of high clinical effects and safty. |
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| Keywords: | Acute viral hepatitis E Tiopronin Liver function index |
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