Identification of genes differentially expressed in monocyte-derived dendritic cells with 1α,25-dihydroxyvitamin D_3 using cDNA arrays |
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引用本文: | 沈倩云,郑树森.Identification of genes differentially expressed in monocyte-derived dendritic cells with 1α,25-dihydroxyvitamin D_3 using cDNA arrays[J].浙江大学学报(B卷英文版),2004(2). |
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作者姓名: | 沈倩云 郑树森 |
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作者单位: | Department of Surgery,the First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003,China,Department of Surgery,the First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003,China |
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摘 要: | INTRODUCTION 1,25-dihydroxyvitamin D31,25(OH)2D3], the biologically active metabolite of vitamin D3, is a secosteroid hormone that not only regulates bone and calcium/phosphate metabolism but also regu-lates a number of other biological activities, in-cluding modulation of the immune response via specific receptors expressed in antigen presenting cells (APC) and activated T cells. Recently, in-creasing evidence showed that the modulatory role of 1,25(OH)2D3 on T cell phenotype and …
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