| Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks |
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| 作者姓名： | 张才乔 乔惠理 |
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| 作者单位： | College of Animal Sciences，Zhejiang University，Hangzhou 310029，China，College of Biology，China Agricultural University，Beijing 100094，China |
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| 基金项目： | Project supported by the National Natural Science Foundation of China (No. 39970535) and Zhejiang (No. 302352) and Beijing Natural Science Foundation (No. 8000001)，China |
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| 摘 要： | INTRODUCTION Polychlorinated biphenyls (PCBs) are members of the halogenated hydrocarbon class of lipophilic environmental endocrine disrupters that includes the dibenzofurans and dioxins. Their appearance in the ecosystem and in the tissues from wildlife, as well as documented cases of accidental poisoning led to the banning of their manufacture in 1977 (Tilson and Kodavanti, 1997). The PCBs continue to be of concern to biologists due to reports that exposure to relatively low levels…
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Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks |
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| ZHANG Cai-qiao,QIAO Hui-li.Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks[J].Journal of Zhejiang University Science,2004(2). |
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| Authors: | ZHANG Cai-qiao QIAO Hui-li |
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| Abstract: | The effects of polychlorinated biphenyls (PCBs) on reproduction of adult cocks were studied by gavaging peanut oil or PCBs (Aroclor 1254, 50 mg/kg) once a week for six consecutive weeks. Physiological parameters were recorded and gonads were removed at the end of experiment for histological examination. The results showed that there was no significant difference between the control and treatment group in body weight, respiration rate, heart rate, body temperature, and the numbers of red and white blood cells. However, there was a marked decrease in the testicular weight and serum testosterone level after PCB treatment. Morphological studies manifested severe damage of the seminiferous tubules by PCB. The number of the germ cells at the different developmental stages was decreased and condensed nuclei were observed in most of these cells. This study revealed that the reproductive function of the adult cocks is sensitive to PCBs, which inhibited mainly spermatogenesis and testosterone secretion. |
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| Keywords: | Chicken Polychlorinated biphenyls (PCBs) Spermatogenesis Testosterone |
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