The role of habituation of the response to LiCl in the US-preexposure effect |
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| Authors: | de Brugada Isabel González Felisa Gil Marta Hall Geoffrey |
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| Institution: | University of Granada, Granada, Spain. dbrugada@ugr.es |
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| Abstract: | In two experiments, rats received preexposure consisting of six intraperitoneal injections of lithium chloride (LiCl). This
treatment reduced the magnitude of the unconditioned response (UR; suppressed consumption of a novel flavor) evoked by an
additional injection (Experiment 1) or by oral consumption (Experiment 2) of LiCl. In both experiments, preexposure also attenuated
the acquisition of a conditioned aversion with an LiCl injection as the unconditioned stimulus (US) but had no effect on the
aversion produced when the US was oral consumption of LiCl (Experiment 2). These results are consistent with the view that
the reduced ability of the preexposed US to serve as a reinforcer depends on blocking by injection-related cues and is independent
of habituation of the UR recorded in the present study. Possible interpretations of this dissociation are discussed. |
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