| α-酮酸的应用及合成研究进展 |
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| 引用本文： | 向纪明.α-酮酸的应用及合成研究进展[J].安康学院学报,2011,23(5):1-5,9. |
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| 作者姓名： | 向纪明 |
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| 作者单位： | 安康学院,陕西安康,725000 |
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| 基金项目： | 安康学院院级科研项目(AZXZ0302) |
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| 摘 要： | α-酮酸是一类双官能团有机化合物，是有机合成、药物合成及生物合成的重要中间体，已广泛应用于食品、化妆品、药物及有机合成中。本文综述了近年来α-酮酸的应用及合成进展情况，其合成方法包括氧化法、水解法、格氏试剂法、羰基化法、海因法及F-C酰基化法，并对这些合成方法及其应用前景进行了讨论。
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| 关 键 词： | α-酮酸酯 合成 应用 综述 |
Applications of Alkyl Arylglyoxylates Derivatives in Organic Synthesis |
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| XIANG Jiming.Applications of Alkyl Arylglyoxylates Derivatives in Organic Synthesis[J].Journal of Ankang Teachers College,2011,23(5):1-5,9. |
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| Authors: | XIANG Jiming |
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| Institution: | (Ankang University,Ankang 725000,Shaanxi,China) |
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| Abstract: | α-Ketoacids are a group of double functional organic compounds and important intermediates to organic synthesis, drug syn- thesis and biological synthesis, their applications in the fields of food, cosmetics, pharmaceutical and organic synthetic industry were stated. The various synthetic methods of α-Ketoaeids at home and abroad were introduced, including the methods of Oxidation, Hy- drolysis, Grlgnard reagents, carbonylation, hydantoin and Friedel-Crafts acylation. The application prospect and the problems existing in current research of ct -Ketoacid were also discussed. |
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| Keywords: | α-keto esters synthesis application review |
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