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稀土联吡啶配合物对黑曲霉活性的影响
引用本文:姚飞虹,肖圣雄,张建军,江琼,陈双喜,黄熠.稀土联吡啶配合物对黑曲霉活性的影响[J].湘南学院学报,2012(2):45-49.
作者姓名:姚飞虹  肖圣雄  张建军  江琼  陈双喜  黄熠
作者单位:湘南学院化学与生命科学系;河北师范大学实验中心
基金项目:国家自然科学基金项目(21073053);湖南省教育厅科研项目(06C784,07C701);湘南学院科研基金(2010Y061)
摘    要:实验采用平皿培养法和抑菌圈法测定了稀土三元配合物RE(2-Cl-4-FBA)3bipy(RE=Nd、Sm、Ho、Eu)以及配体2-氯-4-氟苯甲酸(2-Cl-4-FHBA)、2,2‘-联吡啶(bipy)对黑曲霉生物活性的影响.通过比较抑菌圈直径的大小,发现合成的四种配合物对黑曲霉生长都存在选择性抑制,其中Sm的三元配合物抑制作用最明显;在相同条件下继续培养,每两周测量抑菌圈直径,其结果表明配合物的抑菌效果稳定持久.初步推测可将这种稀土配合物应用于那些具备适宜黑曲霉生长和繁殖条件的工业器械的灭菌.

关 键 词:稀土配合物  2  2‘-联吡啶  卤代苯甲酸  黑曲霉  抑菌圈  选择性抑制  长期抑制特性

Influence of the Rare Earth Complex RE(2-Cl-4-FBA)3 bipy on the Bacteriostatic Activity of Aspergillus Niger
Yao Feihong,Xiao Shengxiong,Zhang Jianjun,Jiang Qiong,Chen Shuangxi,Huang Yi.Influence of the Rare Earth Complex RE(2-Cl-4-FBA)3 bipy on the Bacteriostatic Activity of Aspergillus Niger[J].Journal of Xiangnan University,2012(2):45-49.
Authors:Yao Feihong  Xiao Shengxiong  Zhang Jianjun  Jiang Qiong  Chen Shuangxi  Huang Yi
Institution:1(1 Department of Chemistry and Life Science,Xiangnan University,Chenzhou 423000,China;2 Experimental Center,Hebei Normal University,Shijiazhuang 050016,China)
Abstract:This paper dealt with the influence of the rare earth ternary complex RE(2-Cl-4-FBA)3bipy(RE=Nd,Sm,Ho,Eu)and its ligands(2-Cl-4-FHBA and bipy) on the bacteriostatic activity of Aspergillus niger with the method of plate culture and bacteriostatic circle.The result,comparing the size of bacteriostatic circle,showed that the complex with different ingredients of rare earth had selective inhibition,especially the complex with Sm3+ had better effect than the others.We continued to cultivate the Aspergillus niger we have experimented on under the parallel environment.What is more,through analysing the data,which stemmed from measuring the bacteriostatic cycle diameter every two weeks,we found the bacteriostatic efficacy was stable and lasting at the same time.As a consequence,we can speculate preliminarily that it is possible for us to apply the characteristics of stable bacteriostatic effect of this kind of rare earth ternary complex on the activity of Aspergillus niger to the sterilizing of industry equipment where it is suitable for Aspergillus niger to grow and reproduce.
Keywords:rare earth complex  2  2’-bipyridine  Halobenzoic Acids  Aspergillus niger  bacteriostatic circle  selective inhibition  characteristics of stable bacteriostatic  
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