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腹膜及腹膜后间质瘤11例临床病理分析
引用本文:孙静阳,任欣,于晶功,许朝军,胡波.腹膜及腹膜后间质瘤11例临床病理分析[J].大连大学学报,2005,26(2):78-80,84.
作者姓名:孙静阳  任欣  于晶功  许朝军  胡波
作者单位:1. 大连大学,附属医院,辽宁,大连,116021
2. 大连大学,医学院,辽宁,大连,116622
摘    要:目的]探讨腹膜、腹膜后间质瘤的临床病理特点.方法]对大连大学附属医院近3a收治11例腹膜、腹膜后间质瘤患者的临床病理特点及用免疫组织化学方法检测CD117、CD34、SMA、S100蛋白表达的情况进行回顾性分析.结果]11例患者中发生于结肠(横结肠)上区3例,结肠(横结肠)下区8例.肿瘤未能完整切除者4例.肿瘤大小≤2cm者2例,>2~5cm者1例,>5~10cm者3例,>10cm者5例.细胞形态以梭形细胞为主9例,以上皮样细胞为主2例.11例患者CD117全部阳性,CD34阳性7例,SMA阳性5例,S100全阴性.结论]结果提示腹膜、腹膜后间质瘤作为GIST的一种特殊类型,有着其自身的临床病理特点.

关 键 词:间质瘤  免疫组化  临床病理分析
文章编号:1008-2395(2005)02-0078-04
修稿时间:2005年3月11日

Clinical & pathological analysis of 11 peritoneal or retroperitoneal stromal tumors
SUN Jing-yang,Ren Xin,YU Jing-gong,XU Zhao-jun,HU Bo.Clinical & pathological analysis of 11 peritoneal or retroperitoneal stromal tumors[J].Journal of Dalian University,2005,26(2):78-80,84.
Authors:SUN Jing-yang  Ren Xin  YU Jing-gong  XU Zhao-jun  HU Bo
Abstract:Objective]To investigate the clinical and pathological characteristics of the peritoneal or retroperitoneal stromal tumors.Methods]The clinical pathologic data and the expression of CD117、CD34、SMA、S-100 measured with immunohistochemistry in 11 cases with the peritoneal or retroperitoneal stromal tumors in the late 3 years were studied retrospectively.Results]In the 11 cases,3 locate in the district up the colon,8 locate in the district down the colon.The 4 tumors can’t be cut off completely by surgery.The tumor <2cm(n=2), 2~5cm(n=1),5~10cm(n=3),>10cm(n=5).9 cases mainly show spindly cell type,2 mainly show epithelioid cytologyic feature.In 11 cases,all are CD117 positive,7 are CD34 positive, 5 are SMA positive,none is positive in S-100.Conclusion]The results suggest that the peritoneal or retroperitoneal stromal tumor is an especial kind of GIST,but it has its own clinical and pathological characteristics.
Keywords:stromal tumor  immunohistochemistry  clinical & pathological analysis
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