| 视黄醇结合蛋白4在胰岛素抵抗形成中的作用及其与运动关系的研究进展 |
| |
| 引用本文： | 张明军.视黄醇结合蛋白4在胰岛素抵抗形成中的作用及其与运动关系的研究进展[J].惠州学院学报,2012,32(3):83-90. |
| |
| 作者姓名： | 张明军 |
| |
| 作者单位： | 惠州学院体育系,广东惠州,516007 |
| |
| 基金项目： | 福建省自然科学基金项目，惠州学院博士启动项目 |
| |
| 摘 要： | 对视黄醇结合蛋白4在胰岛素抵抗形成中的作用及其与运动关系的研究进展进行了综述研究。视黄醇结合蛋白4是将肥胖、2型糖尿病胰岛素抵抗联系起来的脂肪因子，视黄醇结合蛋白4遗传多态性亦与胰岛素抵抗的发生关系密切。视黄醇结合蛋白4能够通过抑制胰岛素信号蛋白诱导胰岛素抵抗。运动能够降低正常体重、肥胖、2型糖尿病对象的视黄醇结合蛋白4，改善胰岛素抵抗。
|
| 关 键 词： | 视黄醇结合蛋白4 胰岛素抵抗 肥胖 2型糖尿病 运动 |
Research Progress in Function of Retinol Binding Protein4 on Insulin Resistance Formation and Effects of Exercise on Retinol Binding Protein4 |
| |
| ZHANG Ming-jun.Research Progress in Function of Retinol Binding Protein4 on Insulin Resistance Formation and Effects of Exercise on Retinol Binding Protein4[J].Journal of Huizhou University,2012,32(3):83-90. |
| |
| Authors: | ZHANG Ming-jun |
| |
| Institution: | ZHANG Ming-jun(Department of Physical Education,Huizhou University,Huizhou 516007,Guangdong China) |
| |
| Abstract: | This paper summarizes the function of retinol binding protein 4 on insulin resistance formation and effects of exercise on retinol binding protein 4.RBP4 is an adipocyte-derived ’signal’ that may contribute to the relationship between insulin resistance and obesity,type 2 diabetes.Retinol binding protein4 genetic polymorphism is relevant to insulin resistance formation too.Retinol binding protein4 could induce insulin resistance by suppression insulin signal protein.Exercise decreases retinol binding protein 4 level of normal subjects,obesity,and type 2 diabetes to improve insulin resistance. |
| |
| Keywords: | retinol binding protein4 insulin resistance obesity type 2 diabetes exercise |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
